EFFECTIVENESS OF ROBOTIC BALANCE TRAINING ON POSTURAL INSTABILITY IN PATIENTS WITH MILD PARKINSON’S DISEASE: A PILOT, SINGLE-BLIND, RANDOMIZED CONTROLLED TRIAL

Abstract

Verbatim from Semantic Scholar. Not paraphrased, not summarized.

Objective To examine whether tailored robotic platform training could improve postural stability compared with conventional balance treatment in patients with mild Parkinson’s disease. Design Randomized single-blind pilot study. Subjects Twenty-two patients with mild Parkinson’s disease (Hoehn & Yahr scale; H&Y 1–2). Methods Patients were randomly assigned to an experimental group for robotic balance training and to a control group for conventional balance training. Each patient received 20 treatments (45 min/session, 5 times/week). Blinded evaluations were conducted before and after the treatment and 1 month post-treatment. Primary outcome measures were Mini BESTest, and Berg Balance Scale; secondary outcome measures were 10-Meter Walk Test, Five Times Sit to Stand Test, and Parkinson’s Disease Questionnaire 39. Results Primary outcome measures in patients in both the experimental and control groups improved significantly after the balance treatment. Similar results were found for all the secondary outcome measures. The experimental group performed significantly better than the control group at both post-intervention and follow-up evaluation in the primary outcomes (p < 0.05). No significant differences between groups were found in secondary outcomes. Conclusion Robot-assisted balance training may be a promising tool to improve postural stability in patients with mild Parkinson’s disease. LAY ABSTRACT More than 10 million people worldwide are living with Parkinson’s disease. Parkinson’s disease is a slowly progressive neurodegenerative disorder that leads to balance problems. Balance is a major concern in patients with Parkinson’s disease, and shows poor response to pharmacological treatment. It is known that exercise and physiotherapy can help. The best approach is to start exercising at the early stages of the disease with personalized rehabilitation treatment. This study explored the effectiveness of a new robotic platform treatment on balance compared with the conventional approach. Both trainings were found to improve balance, walking and quality of life. However, robotic balance training could have a major impact. The robotic device enables the training to be intense, fun, task-oriented, challenging and personalized, enhancing motor learning and neuroplasticity. This advance in rehabilitation technology could help to meet the challenges presented by Parkinson’s disease.

Authors

• S. Spina
• Salvatore Facciorusso
• N. Cinone
• Raffaella Armiento
• A. Picelli
• Christian Avvantaggiato
• Chiara Ciritella
• P. Fiore
• A. Santamato

Keywords

• Medicine
• Engineering